Current courses with BIOE attribute

The following courses in the catalog are accepted for the bioengineering minor. Additional courses may be added to the course catalog and not immediately updated here. Please consult the course catalog for the most authoritative list.

Substantially similar courses offered through ND International programs will be considered on a case by case basis.

AME 30386 - Introduction to Bioengineering

This course provides basic science knowledge and engineering practices used by biomedical engineers toward solving problems in human medicine. Topics will include an overview of bioengineering and modern biology, introduction of cell/molecular/genetic engineering principles and the use of engineering analysis to describe living systems, starting with mass and energy balances to understand cell growth and signal transduction. Examples will include the use of general accounting equations (i.e., mass, energy, momentum and charge) toward problems from selected medical engineering fields. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 

AME 40548 - Biofabrication

This course covers materials processing and advanced manufacturing approaches as applied to biomedical science and engineering including photolithography, softlithography, AFM and SEM-based fabrication and 3D micro-nanofabrication for applications such as microfluidics; scaffold production for tissue engineering, studying mechanotransduction and the cellular forces, nanoparticles and nanoscale structures as functional bio-interfaces, peptide-nanoparticle assemblies, nanoparticle-biomolecule hybrids as bioactive materials, self-assembling peptides scaffolds for 3-dimensional tissue / cell cultures, magnetic cell separation to enrich for rare cells. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours  

AME 40571 - Structural Aspects of Biomechanics

Structure and mechanical functions of load bearing tissues and their replacements. Natural and synthetic load-bearing biomaterials for clinical applications are reviewed. Biocompatibility and host response to structural implants are examined. Quantitative treatment of biomechanical issues related to design of biomaterial replacements for structural function. Material selection for reconstructive surgery is addressed. Directions in tissue engineering are presented. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours   

AME 40572 - Introduction to Biomechanics

This course is an introduction to the application of mechanical engineering analysis to understand topics in biology. Topics will include development, disease, diagnosis, treatment, imaging, and mechanical testing in a variety of biological systems across scales. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 

AME 40671 - Orthopaedic Biomechanics

An introduction to the biomechanics of the musculoskeletal system. Kinematics and dynamics of the skeleton. Calculation of inter-segmental forces, muscle forces, and activation levels. Mechanical behavior of typical orthopaedic tissues using appropriate engineering models. Mechanical adaptability of the skeleton to mechanical loads. Applications to the design of arthopaedic devices. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 

AME 60672 - Cell Mechanics

The effects of mechanical loading on cells are examined. Mechanical properties and material structure of cell materials are reviewed. Filaments, filament networks and membranes are examined. Mechanics of flow induced effects, adhesion cell-substrate interactions, and signal transduction are examined. Experimental techniques are reviewed. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 

AME 60673 - Kinematics of Human Motion

To teach students the motion capabilities of the human body and to develop and study kinematic models of the individual joints in the human body. Both simply rotational models and more advanced three dimensional models will be developed for the individual joints. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 

AME 60676 - Cancer Engineering

Applying engineering concepts to cancer biology allows for the design of new models, methods, and technologies for improved diagnostics, monitoring, and treatment. We will explore the barriers in the tumor microenvironment that thwart drug delivery and efficacy and tumor-fighting immune cells. Through didactic lectures, expert seminars, and in-class projects based on the primary literature, we will examine how cutting-edge engineering approaches can be used to overcome these barriers and improve treatment outcomes. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 

AME 60677 - Biomimetic Tissue EG:Challenges & Applications for Microfabricated Cell Biomaterial Constructs

The focus of this course is the growing field of tissue engineering, with highlights from the current challenges in the filed and the emerging applications of engineered tissues. In this course we will first discuss the native tissue formation and maintenance process, and summarize the basic properties of the cells and the natural extracellular matrix that compose the natural tissues. Then, materials and fabrication approaches that have been used to mimic the natural tissue formation and organization for engineering biomimetic tissues will be highlighted. We will emphasize on specific applications of tissue engineering to regenerative medicine as well as new endeavors for engineered tissues such as organs-on-chip, biorobotics, tissue engineered meat and leather. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 

AME 60678 - Biomedical Imaging Modalities

Introduction to major biomedical imaging modalities including X-ray radiography, computed tomography (CT), nuclear medicine (SPECT and PET), magnetic resonance imaging (MRI), and ultrasound. Emphasis on principles, approaches, and applications of each imaging modality. Basic physics and imaging equations of the imaging system; hardware and software; sources of noise and primary artifact; safety and patient risk. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 

AME 60679 - Nanoparticles in Biomedicine

Nanoparticle science and engineering will be introduced including the processing (synthesis and surface modification), structure (physical and molecular), and functional properties (biological, electrical, magnetic, mechanical, optical, X-ray, etc.) that enable biomedical applications in drug delivery, imaging, sensing, and tissue regeneration. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 

AME 60770 - Stem Cell Engineering

This course focuses on basic definition of stem cells, derivation, types, and growth kinetics, including self-renewal, pluripotency, and differentiation. Cellular and molecular organization of a developing tissue, genetic editing, as well as engineering principles that govern complex interactions and control stem cell function will be explored. Finally, requirements for clinical application and current clinical trials of stem cells, as well as ethical aspects of stem cells will be discussed. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 

CBE 30357 - Biotransport

This course is an introduction to momentum transport with applications to biological and medical systems. It will serve as a replacement for CBE 30355 for interested students. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 

CBE 30386 - Introduction to Bioengineering

This course provides basic science knowledge and engineering practices used by biomedical engineers toward solving problems in human medicine. Topics will include an overview of bioengineering and modern biology, introduction of cell/molecular/genetic engineering principles and the use of engineering analysis to describe living systems, starting with mass and energy balances to understand cell growth and signal transduction. Examples will include the use of general accounting equations (i.e., mass, energy, momentum and charge) toward problems from selected medical engineering fields. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 

CBE 40325 - Immunoengineering

The immune system involves the most complex yet most powerful processes in the human body to protect us from both invading foreign pathogens and self-derived challenges. As the basic understanding of immunology is growing, engineers are rapidly designing intelligent and diverse strategies to manipulate the immune system to improve human health. In this course, we will extensively cover the basic concepts of immunology as well as explore the engineering strategies currently used to harness the power of the immune function to develop therapeutic and diagnostic approaches for improved human health. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 

CBE 40456 - Polymer Engineering

A course for seniors and graduate students in science and engineering who are interested in applications of engineering to polymer science and technology. Topics include polymerization reactions and the structure, properties, processing, and production of polymers. (Every year) 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 

CBE 40479 - Introduction to Cellular and Tissue Engineering

This course is divided into two parts. The first half will cover principles of cell and developmental biology that guide current approaches in tissue engineering and regenerative medicine. An emphasis will be placed on the computational and quantitative analysis of biological processes such as cell-cell signaling and morphogenesis. The second half covers techniques involved in cultivating cells for applications in recombinant protein production as well as the design of bioartificial organs and regenerative therapeutics. Optimization techniques for culture medium development will also be covered. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 

CBE 40483 - Topics in Biomolecular Engineering

The objective of this class, intended for both upper level undergraduate and graduate students, is to illustrate the emerging field of bioengineering which fuses molecular life sciences with engineering. The students will gain a fundamental understanding in the principles of how biological systems function, and learn about the innovative approaches that engineers take for diagnosis, treatment, and prevention of diseases, design of novel materials, devices, and processes, and in enhancing environmental health. Topics will include: Biological systems, Cell functions, Molecular scale (what is nano?), Molecular interactions & Multivalency, Synthetic molecules, Molecular biology, -Fermentation, Cell culture, & Combinatorial methods-,Protein purification, Bioinformatics, Biotechnology, Biomedical engineering, Drug delivery, Biosensors 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 

CBE 40487 - Drug Development and Pharmacology

This class covers the biological and engineering aspects of drug development, production, and mode of action. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 

CBE 40571 - Structural Aspects of Biomaterials

Structure and mechanical functions of load bearing tissues and their replacements. Natural and synthetic load-bearing biomaterials for clinical applications are reviewed. Biocompatibility and host response to structural implants are examined. Quantitative treatment of biomechanical issues related to design of biomaterial replacements for structural function. Material selection for reconstructive surgery is addressed. Directions in tissue engineering are presented. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 

CBE 40725 - Principles of Molecular Engineering

The objective of this course, intended for both upper level undergraduate and graduate students, is to illustrate the emerging field of molecular engineering. By fusing concepts from chemistry and materials science, molecular engineering seeks rational design of chemical building blocks for organized systems and materials. Students will gain a fundamental perspective for how non-covalent interactions and designed molecular motifs can dictate the structure, function, and properties of resulting engineered systems. This will include an appreciation for the role on intermolecular forces in governing the behavior of these molecules as they interact with each other and with their environment (typically a solvent). Additionally, illustrative examples will point to the power of strategies rooted in principles of molecular engineering to create highly controlled and functional materials. topics will include: non-covalent interactions, molecular design, thermodynamic driving forces, solvent effects, molecular self-assembly, supramolecular chemistry, molecular & materials characterization techniques, and applications of molecular engineering for diverse uses in energy, medicine, computing, formulation science, industrial applications, and food sciences. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 
  • 0.000 Lab hours 

CBE 40888 - Cellular and Physical Principals of Bioengineering

This course covers the breakdown of biological systems at molecular, cellular and tissue levels. It evolves to the design and synthesis of biomaterials at a molecular scale used in manipulating and targeting biological systems, including biotechnology and biomedical engineering. For these purposes, we will learn what is inside a cell, molecular machines, nerve impulses, binding thermodynamics and kinetics in biological systems, chemical forces and molecular self-assembly. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 
  • 0.000 Lab hours 

CBE 41910 - Biomolecular Engineering Lab

In this course, students are exposed to modern laboratory methods in bioengineering and experimental design. Students gain the knowledge to; develop and execute laboratory protocols, write laboratory reports, and present orally their findings. Space in the lab is limited to 32 students. Students with bio and pre-med interests are given priority. If necessary, students are selected through an application process conducted prior to senior registration. All rising senior CBE students are notified via email of the required application and due date. 

  • 3.000 Credit hours 
  • 0.000 Lecture hours 
  • 4.000 Lab hours 

CE 40355 - Water, Disease, and Global Health

The main emphasis of the course will be to study the diseases important to both the developed and developing world. Basic principles of public health, epidemiology, infectious disease microbiology, immunology, and engineering application will be learned utilizing both local and global examples. Particular emphasis will be given to diseases transmitted by water. As a complement to environmental engineering design classes, this class will focus upon the disease agents removed in properly designed municipal water and waste systems. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 
  • 0.000 Lab hours 

EE 40332 - Introduction to Biophotonics and Biomedical Optics

The goal of this course is to provide students with the knowledge to understand and apply state-of-the-art biomedical optical imaging and sensing techniques. This course will teach the fundamentals of light interactions with biological tissues, the preclinical and clinical applications of biomedical optical image/sensing, and the instrumentation required to do so. Topics explored include diffuse optics, tissue spectroscopy, florescence imaging, optical coherence tomography, confocal and nonlinear microscopy techniques, endoscopy, photoacoustics, and laser surgery. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 
  • 0.000 Lab hours 

EE 40432 - Introduction to Systems Biology

The goal of this course is to highlight elementary design principles inherent in biology. Many of the underlying principles governing biochemical reactions in a living cell can be related to network circuit motifs with multiple inputs/outputs, feedback and feedforward. This course draws on control theory and elementary biology to provide a mathematical framework to understand biological networks. The topics examined in the course are drawn from current research and include: transcription networks, stochastic gene induction, adaptation, oscillators (circadian rhythms), riboswitches, plasticity, metabolism, pattern development and cancer. The course is intended for advanced undergraduates and graduate students. EE 41432 and EE 61632 Lab section registration: Mandatory for Graduate Students Optional for Undergraduates 

  • 3.000 TO 4.000 Credit hours 
  • 3.000 TO 4.000 Lecture hours 
  • 0.000 Lab hours 

EE 47040 - Biomedical Device Engineering

Technical advances at the forefront of physics frequently drives biomedical innovation and improves our understanding and treatment of disease. In this course, we will study the physics behind several modern medical diagnostic, therapeutic, and imaging technologies in the context of the biomedical needs they address. 

  • 3.000 Credit hours 
  • 3.000 Lecture hours 
  • 0.000 Lab hours